| Age Group | Name | Time | Yr Set |
| 18 & Under | Forrest Dillaway | 34:34 | 2001 |
| 19 - 24 | Steve Pizzulli | 31:57 | 1991 |
| 25 - 29 | Jack Cassidy | 32:04 | 1994 |
| 30 - 34 | Kevin Kemmerle | 32:36 | 2016 |
| 35 - 39 | Tim Dunlap | 32:49 | 1993 |
| 40 - 44 | Steve Koch | 34:41 | 2001 |
| 45 - 49 | John Weiss | 35:49 | 1991 |
| 50 - 54 | Richard Webb | 35:57 | 1995 |
| 55 - 59 | Bob Taggart | 38:10 | 1996 |
| 60 - 69 | Richard Webb | 41:40 | 2004 |
| 70 & Over | Vic Zwolak | 44:45 | 2009 |
| | | |
| PNC Bank Run for MS 10k - Women | | | |
| Age Group | Name | Time | Yr Set |
| 18 & Under | Cassie White | 40:42 | 2007 |
| 19 - 24 | Meridith Lambert | 36:20 | 2003 |
| 25 - 29 | Nadine Marks | 36:16 | 2000 |
| 30 - 34 | Ann Wehner | 37:30 | 1992 |
| 35 - 39 | Denise Marini | 38:23 | 1998 |
| 40 - 44 | Caroline Lunger | 39:43 | 1991 |
| 45 - 49 | Jeannie Heath | 42:31 | 2010 |
| 50 - 54 | Debbie Pisan | 43:16 | 2015 |
| 55 - 59 | Gail Breslow | 47:48 | 2011 |
| 60 - 69 | Elaine Pinder | 53:34 | 2017 |
| 70 & Over | Betty Olmstead | 1:24:31 | 2016 |
| | | |
| PNC Bank Run for MS 5k - Men | | | |
| Age Group | Name | Time | Yr Set |
| 13 & Under | Michael Flanagan | 16:58 | 2011 |
| 14 - 18 | Nick Pyle | 16:04 | 2006 |
| 19 - 29 | Luke Arbuchle | 15:29 | 2013 |
| 30 - 39 | Steve Lafferty | 15:48 | 2010 |
| 40 - 49 | Paul Olivere | 16:38 | 2008 |
| 50 - 59 | Maurice Pointer | 17:43 | 2005 |
| 60 - 69 | Brian Richards | 18:56 | 2006 |
| 70 & Over | Tom Ellis | 22:22 | 2023 |
| | | |
| PNC Bank Run for MS 5k - Women | | | |
| Age Group | Name | Time | Yr Set |
| 13 & Under | Beth Kelly | 19:20 | 2003 |
| 14 - 18 | Emily Frydrych | 18:08 | 2011 |
| 19 - 29 | Nadine Marks | 17:29 | 1998 |
| 30 - 39 | Vicki Rudawsky | 16:37 | 2003 |
| 40 - 49 | Kirsten Belair | 18:23 | 2013 |
| 50 - 59 | Eleanor Jones | 21:08 | 2015 |
| 60 - 69 | Mary Holiday | 24:11 | 2015 |
| 70 & Over | Mary Narro | 30:20 | 2023 |
